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Impaired Skeletal Muscle Kynurenine Metabolism in Patients with Chronic Obstructive Pulmonary Disease

Background: Loss of peripheral muscle oxidative phenotype, cognitive impairment, and depression are well-recognized systemic manifestations of chronic obstructive pulmonary disease (COPD). Kynurenine (KYN), known to be associated with disturbed mental health, can be metabolized in muscle by kynureni...

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Detalles Bibliográficos
Autores principales: Gosker, Harry R., Clarke, Gerard, de Theije, Chiel C., Cryan, John F., Schols, Annemie M. W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678819/
https://www.ncbi.nlm.nih.gov/pubmed/31247950
http://dx.doi.org/10.3390/jcm8070915