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Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells

Human intestinal organoids (hIOs), which resemble the human intestine structurally and physiologically, have emerged as a new modality for the study of the molecular and cellular biology of the intestine in vitro. We recently developed an in vitro maturation technique for generating functional hIOs...

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Detalles Bibliográficos
Autores principales: Jung, Kwang Bo, Kwon, Ohman, Lee, Mi-Ok, Lee, Hana, Son, Ye Seul, Habib, Omer, Oh, Jung-Hwa, Cho, Hyun-Soo, Jung, Cho-Rok, Kim, Janghwan, Son, Mi-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678857/
https://www.ncbi.nlm.nih.gov/pubmed/31277507
http://dx.doi.org/10.3390/jcm8070976