STAT5a/b Deficiency Delays, but does not Prevent, Prolactin-Driven Prostate Tumorigenesis in Mice

The canonical prolactin (PRL) Signal Transducer and Activator of Transcription (STAT) 5 pathway has been suggested to contribute to human prostate tumorigenesis via an autocrine/paracrine mechanism. The probasin (Pb)-PRL transgenic mouse models this mechanism by overexpressing PRL specifically in th...

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Detalles Bibliográficos
Autores principales: Boutillon, Florence, Pigat, Natascha, Sackmann Sala, Lucila, Reyes-Gomez, Edouard, Moriggl, Richard, Guidotti, Jacques-Emmanuel, Goffin, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678910/
https://www.ncbi.nlm.nih.gov/pubmed/31269779
http://dx.doi.org/10.3390/cancers11070929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678910/
https://www.ncbi.nlm.nih.gov/pubmed/31269779
http://dx.doi.org/10.3390/cancers11070929

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