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Metabolic Syndrome and Salt-Sensitive Hypertension in Polygenic Obese TALLYHO/JngJ Mice: Role of Na/K-ATPase Signaling

We have demonstrated that Na/K-ATPase acts as a receptor for reactive oxygen species (ROS), regulating renal Na(+) handling and blood pressure. TALLYHO/JngJ (TH) mice are believed to mimic the state of obesity in humans with a polygenic background of type 2 diabetes. This present work is to investig...

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Detalles Bibliográficos
Autores principales: Yan, Yanling, Wang, Jiayan, Chaudhry, Muhammad A., Nie, Ying, Sun, Shuyan, Carmon, Jazmin, Shah, Preeya T., Bai, Fang, Pratt, Rebecca, Brickman, Cameron, Sodhi, Komal, Kim, Jung Han, Pierre, Sandrine, Malhotra, Deepak, Rankin, Gary O., Xie, Zi-jian, Shapiro, Joseph I., Liu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678942/
https://www.ncbi.nlm.nih.gov/pubmed/31315267
http://dx.doi.org/10.3390/ijms20143495