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Harnessing Induced Essentiality: Targeting Carbonic Anhydrase IX and Angiogenesis Reduces Lung Metastasis of Triple Negative Breast Cancer Xenografts

Triple Negative Breast Cancer (TNBC) is aggressive, metastatic and drug-resistant, limiting the spectrum of effective therapeutic options for breast cancer patients. To date, anti-angiogenic agents have had limited success in the treatment of systemic breast cancer, possibly due to the exacerbation...

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Detalles Bibliográficos
Autores principales: Hedlund, Eva-Maria E., McDonald, Paul C., Nemirovsky, Oksana, Awrey, Shannon, Jensen, Lasse D.E., Dedhar, Shoukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678951/
https://www.ncbi.nlm.nih.gov/pubmed/31319613
http://dx.doi.org/10.3390/cancers11071002