Dietary Cholesterol Is Highly Associated with Severity of Hyperlipidemia and Atherosclerotic Lesions in Heterozygous LDLR-Deficient Hamsters

Objective: Familial hypercholesterolemia (FH) is a dominant inherited disease caused mainly by low-density lipoprotein receptor (LDLR) gene mutations. To different extents, both heterozygous and homozygous FH patients develop premature coronary heart disease (CHD). However, most of the experimental...

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Detalles Bibliográficos
Autores principales: Wang, Jinjie, He, Kunxiang, Yang, Chun, Lin, Xiao, Zhang, Xin, Wang, Yuhui, Liu, George, Xian, Xunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678973/
https://www.ncbi.nlm.nih.gov/pubmed/31323736
http://dx.doi.org/10.3390/ijms20143515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678973/
https://www.ncbi.nlm.nih.gov/pubmed/31323736
http://dx.doi.org/10.3390/ijms20143515

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