Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains

Inside the female genital tract, mammalian sperm undergo a maturation process called capacitation, which primes the sperm to navigate across the oviduct and fertilize the egg. Sperm capacitation and motility are controlled by 3′,5′-cyclic adenosine monophosphate (cAMP). Here, we show that optogeneti...

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Detalles Bibliográficos
Autores principales: Raju, Diana N., Hansen, Jan N., Rassmann, Sebastian, Stüven, Birthe, Jikeli, Jan F., Strünker, Timo, Körschen, Heinz G., Möglich, Andreas, Wachten, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679001/
https://www.ncbi.nlm.nih.gov/pubmed/31252584
http://dx.doi.org/10.3390/cells8070648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679001/
https://www.ncbi.nlm.nih.gov/pubmed/31252584
http://dx.doi.org/10.3390/cells8070648

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