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Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains
Inside the female genital tract, mammalian sperm undergo a maturation process called capacitation, which primes the sperm to navigate across the oviduct and fertilize the egg. Sperm capacitation and motility are controlled by 3′,5′-cyclic adenosine monophosphate (cAMP). Here, we show that optogeneti...
Autores principales: | Raju, Diana N., Hansen, Jan N., Rassmann, Sebastian, Stüven, Birthe, Jikeli, Jan F., Strünker, Timo, Körschen, Heinz G., Möglich, Andreas, Wachten, Dagmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679001/ https://www.ncbi.nlm.nih.gov/pubmed/31252584 http://dx.doi.org/10.3390/cells8070648 |
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