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Profiling the Stromal and Vascular Heterogeneity in Patient-derived Xenograft Models of Head and Neck Cancer: Impact on Therapeutic Response

Head and neck squamous cell carcinomas (HNSCC) represent a group of epithelial neoplasms that exhibit considerable heterogeneity in clinical behavior. Here, we examined the stromal and vascular heterogeneity in a panel of patient-derived xenograft (PDX) models of HNSCC and the impact on therapeutic...

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Detalles Bibliográficos
Autores principales: Folaron, Margaret, Merzianu, Mihai, Duvvuri, Umamaheswar, Ferris, Robert L., Seshadri, Mukund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679003/
https://www.ncbi.nlm.nih.gov/pubmed/31284584
http://dx.doi.org/10.3390/cancers11070951