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Whole Genome Microarray Analysis of DUSP4-Deletion Reveals A Novel Role for MAP Kinase Phosphatase-2 (MKP-2) in Macrophage Gene Expression and Function

Background: Mitogen-activated protein kinase phosphatase-2 (MKP-2) is a type 1 nuclear dual specific phosphatase (DUSP-4). It plays an important role in macrophage inflammatory responses through the negative regulation of Mitogen activated protein kinase (MAPK) signalling. However, information on th...

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Detalles Bibliográficos
Autores principales: Neamatallah, Thikryat, Jabbar, Shilan, Tate, Rothwelle, Schroeder, Juliane, Shweash, Muhannad, Alexander, James, Plevin, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679025/
https://www.ncbi.nlm.nih.gov/pubmed/31336892
http://dx.doi.org/10.3390/ijms20143434