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RNase L Induces Expression of A Novel Serine/Threonine Protein Kinase, DRAK1, to Promote Apoptosis

Apoptosis of virus-infected cells is an effective antiviral mechanism in addition to interferon induction to establish antiviral state to restrict virus spread. The interferon-inducible 2′–5′ oligoadenylate synthetase/RNase L pathway results in activation of RNase L in response to double stranded RN...

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Detalles Bibliográficos
Autores principales: Manivannan, Praveen, Reddy, Vidita, Mukherjee, Sushovita, Clark, Kirsten Neytania, Malathi, Krishnamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679093/
https://www.ncbi.nlm.nih.gov/pubmed/31330998
http://dx.doi.org/10.3390/ijms20143535