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RNase L Induces Expression of A Novel Serine/Threonine Protein Kinase, DRAK1, to Promote Apoptosis
Apoptosis of virus-infected cells is an effective antiviral mechanism in addition to interferon induction to establish antiviral state to restrict virus spread. The interferon-inducible 2′–5′ oligoadenylate synthetase/RNase L pathway results in activation of RNase L in response to double stranded RN...
Autores principales: | Manivannan, Praveen, Reddy, Vidita, Mukherjee, Sushovita, Clark, Kirsten Neytania, Malathi, Krishnamurthy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679093/ https://www.ncbi.nlm.nih.gov/pubmed/31330998 http://dx.doi.org/10.3390/ijms20143535 |
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