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Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance

Circulating tumor cells (CTCs) hold great promise with regard to prognosis, treatment optimization, and monitoring of breast cancer patients. Single CTC transcriptome profiling might help reveal valuable information concerning intra-patient heterogeneity relevant to therapeutic interventions. In thi...

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Detalles Bibliográficos
Autores principales: Reinhardt, Florian, Franken, André, Meier-Stiegen, Franziska, Driemel, Christiane, Stoecklein, Nikolas H., Fischer, Johannes C., Niederacher, Dieter, Ruckhaeberle, Eugen, Fehm, Tanja, Neubauer, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679140/
https://www.ncbi.nlm.nih.gov/pubmed/31261643
http://dx.doi.org/10.3390/cancers11070903