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Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer

Acquired paclitaxel (PTX) resistance limits its effectiveness and results in advanced cancer progression. This review investigated whether the inhibition of phosphatidylinositol 3-kinase (PI3K) signaling overcomes paclitaxel resistance in cervical cancer. It was established paclitaxel-resistant cell...

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Detalles Bibliográficos
Autores principales: Liu, Jing Jing, Ho, Jung Yoon, Lee, Hye Won, Baik, Min Wha, Kim, Oyoung, Choi, Youn Jin, Hur, Soo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679163/
https://www.ncbi.nlm.nih.gov/pubmed/31295843
http://dx.doi.org/10.3390/ijms20143383