Uncovering Potential Therapeutic Targets in Colorectal Cancer by Deciphering Mutational Status and Expression of Druggable Oncogenes

Background: Numerous driver mutations have been identified in colorectal cancer (CRC), but their relevance to the development of targeted therapies remains elusive. The secondary effects of pathogenic driver mutations on downstream signaling pathways offer a potential approach for the identification...

Descripción completa

Detalles Bibliográficos
Autores principales: Menyhart, Otília, Kakisaka, Tatsuhiko, Pongor, Lőrinc Sándor, Uetake, Hiroyuki, Goel, Ajay, Győrffy, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679198/
https://www.ncbi.nlm.nih.gov/pubmed/31337155
http://dx.doi.org/10.3390/cancers11070983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679198/
https://www.ncbi.nlm.nih.gov/pubmed/31337155
http://dx.doi.org/10.3390/cancers11070983

Ejemplares similares