Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance

To define renal molecular mechanisms that are affected by permanent hyperglycaemia and might promote phenotypes relevant to diabetic nephropathy, we carried out linkage analysis of genome-wide gene transcription in the kidneys of F2 offspring from the Goto-Kakizaki (GK) rat model of type 2 diabetes...

Descripción completa

Detalles Bibliográficos
Autores principales: Otto, Georg W., Kaisaki, Pamela J., Brial, Francois, Le Lay, Aurélie, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679378/
https://www.ncbi.nlm.nih.gov/pubmed/31213483
http://dx.doi.org/10.1242/dmm.038539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679378/
https://www.ncbi.nlm.nih.gov/pubmed/31213483
http://dx.doi.org/10.1242/dmm.038539

Ejemplares similares