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Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance
To define renal molecular mechanisms that are affected by permanent hyperglycaemia and might promote phenotypes relevant to diabetic nephropathy, we carried out linkage analysis of genome-wide gene transcription in the kidneys of F2 offspring from the Goto-Kakizaki (GK) rat model of type 2 diabetes...
Autores principales: | Otto, Georg W., Kaisaki, Pamela J., Brial, Francois, Le Lay, Aurélie, Cazier, Jean-Baptiste, Mott, Richard, Gauguier, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679378/ https://www.ncbi.nlm.nih.gov/pubmed/31213483 http://dx.doi.org/10.1242/dmm.038539 |
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