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Genome-wide analysis of androgen receptor binding and transcriptomic analysis in mesenchymal subsets during prostate development

Prostate development is controlled by androgens, the androgen receptor (AR) and mesenchymal–epithelial signalling. We used chromatin immunoprecipitation sequencing (ChIP-seq) to define AR genomic binding in the male and female mesenchyme. Tissue- and single-cell-based transcriptional profiling was u...

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Detalles Bibliográficos
Autores principales: Nash, Claire, Boufaied, Nadia, Badescu, Dunarel, Wang, Yu Chang, Paliouras, Miltiadis, Trifiro, Mark, Ragoussis, Ioannis, Thomson, Axel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679388/
https://www.ncbi.nlm.nih.gov/pubmed/31350272
http://dx.doi.org/10.1242/dmm.039297