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Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells

Differentiation of stem cells to hepatocytes provides an unlimited supply of human hepatocytes and therefore has been vigorously studied. However, to date, the stem cell-derived hepatocytes were suggested to be of immature features. To obtain matured hepatocytes from stem cells, we tested the effect...

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Detalles Bibliográficos
Autores principales: Nakai, Shun, Shibata, Ima, Shitamichi, Takahiro, Yamaguchi, Hiroyuki, Takagi, Nobuyuki, Inoue, Tomoaki, Nakagawa, Toshito, Kiyokawa, Jumpei, Wakabayashi, Satoshi, Miyoshi, Tomoya, Higashi, Eriko, Ishida, Seiichi, Shiraki, Nobuaki, Kume, Shoen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679405/
https://www.ncbi.nlm.nih.gov/pubmed/31182631
http://dx.doi.org/10.1242/bio.042192