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The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts

The heterogeneous properties of dermal cell populations have been posited to contribute toward fibrotic, imperfect wound healing in mammals. Here we characterize an adult population of dermal fibroblasts that maintain an active Prrx1 enhancer which originally marked mesenchymal limb progenitors. In...

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Detalles Bibliográficos
Autores principales: Currie, Joshua D., Grosser, Lidia, Murawala, Prayag, Schuez, Maritta, Michel, Martin, Tanaka, Elly M., Sandoval-Guzmán, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679413/
https://www.ncbi.nlm.nih.gov/pubmed/31278164
http://dx.doi.org/10.1242/bio.043711