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The roles of kinetochore of micronucleus in mitosis of HeLa cells: a live cell imaging study

BACKGROUND: Micronuclei (MNi) are extensively used to evaluate genotoxic effects and chromosome instability. However, the roles of kinetochore of MN in mitosis have not been completely addressed. METHODS: The HeLa CENP B-GFP H2B-mCherry cells are applied to address these questions via the long-term...

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Detalles Bibliográficos
Autores principales: Jiang, Erkang, Wei, Lianping, Tao, Fang, Yu, Mei, Wang, Shu, Zhou, Xiuhong, Li, Daxiang, Xie, Zhongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679434/
https://www.ncbi.nlm.nih.gov/pubmed/31388333
http://dx.doi.org/10.1186/s12935-019-0917-8