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Requirement of the transcription factor YB-1 for maintaining the stemness of cancer stem cells and reverting differentiated cancer cells into cancer stem cells

BACKGROUND: Cancer stem cells always express high levels of stemness-associated transcription factors to maintain their features. However, the regulatory mechanism of the stemness of cancer stem cells mediated by transcription factors has not been extensively explored. METHODS: The YB-1 gene in canc...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Cui, Pei, Lu, Yu, Zhang, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679460/
https://www.ncbi.nlm.nih.gov/pubmed/31375149
http://dx.doi.org/10.1186/s13287-019-1360-4