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Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II–dependent kidney damage

BACKGROUND: Renal proximal tubular sodium and glucose reabsorption are regulated by the sodium-glucose cotransporter (SGLT2). Changes in this transporter can play a role in hyperglycaemia and reactive oxygen species (ROS) production. We demonstrated increased glucose absorption in proximal tubule me...

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Detalles Bibliográficos
Autores principales: Reyes-Pardo, Humberto, Bautista, Rocío, Vargas-Robles, Hilda, Rios, Amelia, Sánchez, Daniel, Escalante, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679465/
https://www.ncbi.nlm.nih.gov/pubmed/31375080
http://dx.doi.org/10.1186/s12882-019-1490-z