Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity

BACKGROUND: MAPK/ERK kinases transmit signals from many growth factors/kinase receptors during normal cell growth/differentiation, and their dysregulation is a hallmark of diverse types of cancers. A plethora of drugs were developed to block this kinase pathway for clinical application. With the exc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ning, Fan, Yanhua, Yuan, Chun-Mao, Song, Jialei, Yao, Yao, Liu, Wuling, Gajendran, Babu, Zacksenhaus, Eldad, Li, Yanmei, Liu, Jielin, Hao, Xiao Jiang, Ben-David, Yaacov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679490/
https://www.ncbi.nlm.nih.gov/pubmed/31375085
http://dx.doi.org/10.1186/s12885-019-5914-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679490/
https://www.ncbi.nlm.nih.gov/pubmed/31375085
http://dx.doi.org/10.1186/s12885-019-5914-8

Ejemplares similares