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Unlike calorie restriction, Roux-en-Y gastric bypass surgery does not increase hypothalamic AgRP and NPY in mice on a high-fat diet

OBJECTIVES: Dieting often fails because weight loss triggers strong counter-regulatory biological responses such as increased hunger and hypometabolism that are thought to be critically dependent on the master fuel sensor in the mediobasal hypothalamus (MBH). Because prolonged starvation has been sh...

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Detalles Bibliográficos
Autores principales: Patkar, Presheet P., Hao, Zheng, Mumphrey, Michael B., Townsend, R. Leigh, Berthoud, Hans-Rudolf, Shin, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679822/
https://www.ncbi.nlm.nih.gov/pubmed/30718818
http://dx.doi.org/10.1038/s41366-019-0328-x