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Galphimia glauca and Natural Galphimines Block Schizophrenia-Like Symptoms Induced with Apomorphine and MK-801 in Mice

BACKGROUND: Galphimia glauca has been used for many years in Mexican Traditional Medicine to calm “insane people.” Triterpenes, known as galphimines, were identified in this species. One of them, Galphimine-B (G-B), acts selectively on dopaminergic neurons by antagonizing the effect of glutamate on...

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Detalles Bibliográficos
Autores principales: Santillán-Urquiza, Mayra Alejandra, Herrera-Ruiz, Maribel, Zamilpa, Alejandro, Jiménez-Ferrer, Enrique, Román-Ramos, Rubén, Alegría-Herrera, Elian Yuritzi, Tortoriello, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679897/
https://www.ncbi.nlm.nih.gov/pubmed/31428176
http://dx.doi.org/10.1155/2019/8404258