Pristimerin induces apoptosis and autophagy via activation of ROS/ASK1/JNK pathway in human breast cancer in vitro and in vivo

Breast cancer is the most common malignant tumor in women, and progress toward long-term survival has stagnated. Pristimerin, a natural quinonemethide triterpenoid, exhibits potential anti-tumor effects on various cancers. However, the underlying mechanism remains poorly understood. In this study, w...

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Detalles Bibliográficos
Autores principales: Zhao, Qun, Liu, Yingxiang, Zhong, Jing, Bi, Yun, Liu, Yongqiang, Ren, Ziting, Li, Xiang, Jia, Junjun, Yu, Mengting, Yu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680048/
https://www.ncbi.nlm.nih.gov/pubmed/31396402
http://dx.doi.org/10.1038/s41420-019-0208-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680048/
https://www.ncbi.nlm.nih.gov/pubmed/31396402
http://dx.doi.org/10.1038/s41420-019-0208-0

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