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C-Jun drives melanoma progression in PTEN wild type melanoma cells

Due to the critical impact of active AP-1 transcription factors in melanoma, it is important to define their target genes and to identify and ultimately inhibit oncogenic signals. Here we mapped the genome-wide occupancy of the AP-1 family member c-Jun in different melanoma cells and correlated AP-1...

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Detalles Bibliográficos
Autores principales: Kappelmann-Fenzl, Melanie, Gebhard, Claudia, Matthies, Alexander O., Kuphal, Silke, Rehli, Michael, Bosserhoff, Anja Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680049/
https://www.ncbi.nlm.nih.gov/pubmed/31378787
http://dx.doi.org/10.1038/s41419-019-1821-9