A specific proteinase 3 activity footprint in α(1)-antitrypsin deficiency

α(1)-Antitrypsin (α(1)-AT) deficiency is a risk factor for emphysema due to tissue damage by serine proteases. Neutrophil elastase (NE) has long been considered the enzyme responsible. However, proteinase 3 (PR3) also produces the pathological features of chronic obstructive pulmonary disease (COPD)...

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Detalles Bibliográficos
Autores principales: Newby, Paul R., Crossley, Diana, Crisford, Helena, Stockley, James A., Mumford, Richard A., Carter, Richard I., Bolton, Charlotte E., Hopkinson, Nicholas S., Mahadeva, Ravi, Steiner, Michael C., Wilkinson, Tom M.A., Sapey, Elizabeth, Stockley, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680069/
https://www.ncbi.nlm.nih.gov/pubmed/31403052
http://dx.doi.org/10.1183/23120541.00095-2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680069/
https://www.ncbi.nlm.nih.gov/pubmed/31403052
http://dx.doi.org/10.1183/23120541.00095-2019

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