IL‐7‐dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti‐tumour response

How the age‐associated decline of immune function leads to increased cancer incidence is poorly understood. Here, we have characterised the cellular composition of the γδ T‐cell pool in peripheral lymph nodes (pLNs) upon ageing. We find that ageing has minimal cell‐intrinsic effects on function and...

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Detalles Bibliográficos
Autores principales: Chen, Hung‐Chang, Eling, Nils, Martinez‐Jimenez, Celia Pilar, O'Brien, Louise McNeill, Carbonaro, Valentina, Marioni, John C, Odom, Duncan T, de la Roche, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680116/
https://www.ncbi.nlm.nih.gov/pubmed/31283095
http://dx.doi.org/10.15252/embr.201847379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680116/
https://www.ncbi.nlm.nih.gov/pubmed/31283095
http://dx.doi.org/10.15252/embr.201847379

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