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IL‐7‐dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti‐tumour response
How the age‐associated decline of immune function leads to increased cancer incidence is poorly understood. Here, we have characterised the cellular composition of the γδ T‐cell pool in peripheral lymph nodes (pLNs) upon ageing. We find that ageing has minimal cell‐intrinsic effects on function and...
Autores principales: | Chen, Hung‐Chang, Eling, Nils, Martinez‐Jimenez, Celia Pilar, O'Brien, Louise McNeill, Carbonaro, Valentina, Marioni, John C, Odom, Duncan T, de la Roche, Maike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680116/ https://www.ncbi.nlm.nih.gov/pubmed/31283095 http://dx.doi.org/10.15252/embr.201847379 |
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