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Efficient Synthesis of Trifluoromethyl Amines through a Formal Umpolung Strategy from the Bench‐Stable Precursor (Me(4)N)SCF(3)
Reported herein is the one‐pot synthesis of trifluoromethylated amines at room temperature using the bench‐stable (Me(4)N)SCF(3) reagent and AgF. The method is rapid, operationally simple and highly selective. It proceeds via a formal umpolung reaction of the SCF(3) with the amine, giving quantitati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680219/ https://www.ncbi.nlm.nih.gov/pubmed/27936300 http://dx.doi.org/10.1002/anie.201609480 |