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EP3 receptor antagonist L798,106 reduces proliferation and migration of SK-BR-3 breast cancer cells
Purpose: COX-2 overexpression and elevated levels of prostaglandin E2 (PGE2) play an important role in breast cancer carcinogenesis. Recently, expression of the PGE2 receptor EP3 has been shown to be a positive prognostic factor in breast cancer. This study analyzes the functional aspects of targeti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680222/ https://www.ncbi.nlm.nih.gov/pubmed/31534346 http://dx.doi.org/10.2147/OTT.S204919 |