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Odanacatib increases mineralized callus during fracture healing in a rabbit ulnar osteotomy model

The effects of the cathepsin K inhibitor odanacatib (ODN) on fracture healing were monitored for ∼6 and 15 weeks post‐fracture in two separate studies using the unilateral transverse mid‐ulnar osteotomy model in skeletally mature female rabbits. Rabbits were pre‐treated for 3–4 weeks with vehicle (V...

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Detalles Bibliográficos
Autores principales: Pennypacker, Brenda L., Gilberto, David, Gatto, Nicholas T., Samadfam, Rana, Smith, Susan Y., Kimmel, Donald B., Duong, Le Thi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680236/
https://www.ncbi.nlm.nih.gov/pubmed/26178170
http://dx.doi.org/10.1002/jor.22982