Isothiourea‐Catalysed Acylative Kinetic Resolution of Aryl–Alkenyl (sp(2) vs. sp(2)) Substituted Secondary Alcohols

The non‐enzymatic acylative kinetic resolution of challenging aryl–alkenyl (sp(2) vs. sp(2)) substituted secondary alcohols is described, with effective enantiodiscrimination achieved using the isothiourea organocatalyst HyperBTM (1 mol %) and isobutyric anhydride. The kinetic resolution of a wide r...

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Detalles Bibliográficos
Autores principales: Musolino, Stefania F., Ojo, O. Stephen, Westwood, Nicholas J., Taylor, James E., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680239/
https://www.ncbi.nlm.nih.gov/pubmed/27775200
http://dx.doi.org/10.1002/chem.201604788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680239/
https://www.ncbi.nlm.nih.gov/pubmed/27775200
http://dx.doi.org/10.1002/chem.201604788

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