Cargando…

Isothiourea‐Catalysed Acylative Kinetic Resolution of Aryl–Alkenyl (sp(2) vs. sp(2)) Substituted Secondary Alcohols

The non‐enzymatic acylative kinetic resolution of challenging aryl–alkenyl (sp(2) vs. sp(2)) substituted secondary alcohols is described, with effective enantiodiscrimination achieved using the isothiourea organocatalyst HyperBTM (1 mol %) and isobutyric anhydride. The kinetic resolution of a wide r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Musolino, Stefania F., Ojo, O. Stephen, Westwood, Nicholas J., Taylor, James E., Smith, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680239/ https://www.ncbi.nlm.nih.gov/pubmed/27775200 http://dx.doi.org/10.1002/chem.201604788

Ejemplares similares

Enantioselective isothiourea-catalysed reversible Michael addition of aryl esters to 2-benzylidene malononitriles
por: Nimmo, Alastair J., et al.
Publicado: (2023)

Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies
por: Stark, Daniel G., et al.
Publicado: (2016)

Isothiourea‐Catalyzed Acylative Kinetic Resolution of Tertiary α‐Hydroxy Esters
por: Qu, Shen, et al.
Publicado: (2020)

Isothiourea-catalysed enantioselective Michael addition of N-heterocyclic pronucleophiles to α,β-unsaturated aryl esters
por: Shu, Chang, et al.
Publicado: (2019)

Asymmetric Isothiourea-Catalysed Formal [3+2] Cycloadditions of Ammonium Enolates with Oxaziridines
por: Smith, Siobhan R, et al.
Publicado: (2015)

Enantioselective Stereodivergent Nucleophile‐Dependent Isothiourea‐Catalysed Domino Reactions
por: Matviitsuk, Anastassia, et al.
Publicado: (2016)

Boron-catalysed transition-metal-free arylation and alkenylation of allylic alcohols with boronic acids
por: Lu, Sixian, et al.
Publicado: (2023)

Chiral isothiourea-catalyzed kinetic resolution of 4-hydroxy[2.2]paracyclophane
por: Weinzierl, David, et al.
Publicado: (2021)

Highly Efficient Kinetic Resolution of Aryl-Alkenyl Alcohols by Ru-Catalyzed Hydrogen Transfer
por: You, Yipeng, et al.
Publicado: (2021)

Regio- and Enantioselective (Het)arylation of β-Alkenyl Pyrroline to α-Aryl-β-alkenyl Pyrrolidines
por: Dwari, Soumita, et al.
Publicado: (2019)

Gold-catalyzed alkenylation and arylation of phosphorothioates
por: Urvashi, et al.
Publicado: (2023)

Rapid and Direct Photocatalytic C(sp(3))−H Acylation and Arylation in Flow
por: Mazzarella, Daniele, et al.
Publicado: (2021)

Lipase-catalysed acylation of starch and determination of the degree of substitution by methanolysis and GC
por: Alissandratos, Apostolos, et al.
Publicado: (2010)

Enantioselective Synthesis of α‐Aryl‐β(2)‐Amino‐Esters by Cooperative Isothiourea and Brønsted Acid Catalysis
por: Zhao, Feng, et al.
Publicado: (2021)

Visible light-mediated gold-catalysed carbon(sp(2))–carbon(sp) cross-coupling
por: Kim, Suhong, et al.
Publicado: (2016)

Isothiourea-Catalyzed Enantioselective Michael Addition of Malonates to α,β-Unsaturated Aryl Esters
por: Wu, Jiufeng, et al.
Publicado: (2022)

Boryl substitution of functionalized aryl-, heteroaryl- and alkenyl halides with silylborane and an alkoxy base: expanded scope and mechanistic studies
por: Yamamoto, Eiji, et al.
Publicado: (2015)

Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles
por: Formica, Michele, et al.
Publicado: (2018)

Mn(ii)-Catalysed ortho-alkenylation of aromatic amines and its application in reproductive diseases
por: Yang, Jinfei, et al.
Publicado: (2020)

Enantioselective synthesis of α-aminoboronates by NiH-catalysed asymmetric hydroamidation of alkenyl boronates
por: Zhang, Yao, et al.
Publicado: (2022)

Rhodium-catalysed C(sp(2))–C(sp(2)) bond formation via C–H/C–F activation
por: Tian, Panpan, et al.
Publicado: (2015)

Triarylborane‐Catalyzed Alkenylation Reactions of Aryl Esters with Diazo Compounds
por: Dasgupta, Ayan, et al.
Publicado: (2020)

Photoinduced site-selective alkenylation of alkanes and aldehydes with aryl alkenes
por: Cao, Hui, et al.
Publicado: (2020)

Palladium-Catalyzed N-Alkenylation of N-Aryl Phosphoramidates with Alkenes
por: Li, Yu-An, et al.
Publicado: (2023)

Iron-Catalysed C(sp(2))-H Borylation Enabled by Carboxylate Activation
por: Britton, Luke, et al.
Publicado: (2020)

Palladium-catalysed C–H arylation of benzophospholes with aryl halides
por: Xu, Shibo, et al.
Publicado: (2022)

Enantioselective nickel-catalyzed arylative and alkenylative intramolecular 1,2-allylations of tethered allene–ketones
por: Di Sanza, Riccardo, et al.
Publicado: (2020)

Hindered aryl bromides for regioselective palladium-catalysed direct arylation at less favourable C5-carbon of 3-substituted thiophenes
por: Jin, Rongwei, et al.
Publicado: (2014)

Enantioselective Synthesis of 3,5,6‐Substituted Dihydropyranones and Dihydropyridinones using Isothiourea‐Mediated Catalysis
por: Stark, Daniel G., et al.
Publicado: (2015)

C(sp(3))–C(sp(2)) cross-coupling of alkylsilicates with borylated aryl bromides – an iterative platform to alkylated aryl- and heteroaryl boronates
por: Vara, Brandon A., et al.
Publicado: (2017)

C(sp(3))-Arylation by Conformationally Accelerated Intramolecular Nucleophilic Aromatic Substitution (S(N)Ar)
por: Wales, Steven M., et al.
Publicado: (2022)

A practical preparation of bicyclic boronates via metal-free heteroatom-directed alkenyl sp(2)-C‒H borylation
por: Peng, Pei-Ying, et al.
Publicado: (2023)

C(acyl)–C(sp(2)) and C(sp(2))–C(sp(2)) Suzuki–Miyaura cross-coupling reactions using nitrile-functionalized NHC palladium complexes
por: Çakır, Sinem, et al.
Publicado: (2021)

Transition metal-free domino acyl substitution/Michael addition of alkenyl Grignard reagents to lactam esters: synthesis of lactam-bearing homoallylic ketones
por: Farah, Abdikani Omar, et al.
Publicado: (2020)

Continuous Flow Sodiation of Substituted Acrylonitriles, Alkenyl Sulfides and Acrylates
por: Harenberg, Johannes H., et al.
Publicado: (2020)

Stereoselective Csp(3)−Csp(2) Cross‐Couplings of Chiral Secondary Alkylzinc Reagents with Alkenyl and Aryl Halides
por: Skotnitzki, Juri, et al.
Publicado: (2019)

Mechanism, Reactivity, and Selectivity in Palladium-Catalyzed Redox-Relay Heck Arylations of Alkenyl Alcohols
por: Xu, Liping, et al.
Publicado: (2014)

Nickel-Catalyzed Enantioselective Electrochemical Reductive Cross-Coupling of Aryl Aziridines with Alkenyl Bromides
por: Hu, Xia, et al.
Publicado: (2023)

Iron-Catalyzed C(sp(2))–C(sp(3)) Cross-Coupling of Aryl Chlorobenzoates with Alkyl Grignard Reagents
por: Bisz, Elwira, et al.
Publicado: (2020)

Temperature-modulated selective C(sp(3))–H or C(sp(2))–H arylation through palladium catalysis
por: Gogula, Thirupathi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h281gsq06m3get7ggd9kq3o4q2