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Thymidylate synthase expression in circulating tumor cells: A new tool to predict 5‐fluorouracil resistance in metastatic colorectal cancer patients

Thymidylate synthase (TYMS) is an important enzyme for 5‐fluorouracil (5‐FU) metabolism in metastatic colorectal cancer (mCRC) patients. The search for this enzyme in circulating tumor cells (CTCs) can be a powerful tool to follow‐up cancer patients. mCRC patients were enrolled before the beginning...

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Detalles Bibliográficos
Autores principales: Abdallah, Emne Ali, Fanelli, Marcello Ferretti, Buim, Marcilei Eliza Cavicchioli, Machado Netto, Marcelo Calil, Gasparini Junior, José Luiz, Souza e Silva, Virgílio, Dettino, Aldo Lourenço Abbade, Mingues, Natalia Breve, Romero, Juliana Valim, Ocea, Luciana Menezes Mendonça, Rocha, Bruna Maria Malagoli, Alves, Vanessa Silva, Araújo, Daniel Vilarim, Chinen, Ludmilla Thomé Domingos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680263/
https://www.ncbi.nlm.nih.gov/pubmed/25721610
http://dx.doi.org/10.1002/ijc.29495