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Self‐Assembly of Measles Virus Nucleocapsid‐like Particles: Kinetics and RNA Sequence Dependence

Measles virus RNA genomes are packaged into helical nucleocapsids (NCs), comprising thousands of nucleo‐proteins (N) that bind the entire genome. N‐RNA provides the template for replication and transcription by the viral polymerase and is a promising target for viral inhibition. Elucidation of mecha...

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Detalles Bibliográficos
Autores principales: Milles, Sigrid, Jensen, Malene Ringkjøbing, Communie, Guillaume, Maurin, Damien, Schoehn, Guy, Ruigrok, Rob W. H., Blackledge, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680290/
https://www.ncbi.nlm.nih.gov/pubmed/27270664
http://dx.doi.org/10.1002/anie.201602619