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Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer

BACKGROUND: In vitro and experimental animal studies have demonstrated that high levels of omega‐6 (n‐6) polyunsaturated fatty acids (PUFAs) and high ratios of n‐6 to omega‐3 (n‐3) PUFAs are strongly associated with the development and progression of prostate cancer (PCA). However, epidemiological s...

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Detalles Bibliográficos
Autores principales: Cui, Tao, Hester, Austin G., Seeds, Michael C., Rahbar, Elaheh, Howard, Timothy D., Sergeant, Susan, Chilton, Floyd H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680327/
https://www.ncbi.nlm.nih.gov/pubmed/27197070
http://dx.doi.org/10.1002/pros.23205