Cargando…

Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer

BACKGROUND: In vitro and experimental animal studies have demonstrated that high levels of omega‐6 (n‐6) polyunsaturated fatty acids (PUFAs) and high ratios of n‐6 to omega‐3 (n‐3) PUFAs are strongly associated with the development and progression of prostate cancer (PCA). However, epidemiological s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Tao, Hester, Austin G., Seeds, Michael C., Rahbar, Elaheh, Howard, Timothy D., Sergeant, Susan, Chilton, Floyd H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680327/ https://www.ncbi.nlm.nih.gov/pubmed/27197070 http://dx.doi.org/10.1002/pros.23205

Ejemplares similares

Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster
por: Rahbar, Elaheh, et al.
Publicado: (2017)

Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression
por: Reynolds, Lindsay M., et al.
Publicado: (2018)

Impact of FADS gene variation and dietary fatty acid exposure on biochemical and anthropomorphic phenotypes in a Hispanic/Latino cohort
por: Sergeant, Susan, et al.
Publicado: (2023)

DNA Methylation in an Enhancer Region of the FADS Cluster Is Associated with FADS Activity in Human Liver
por: Howard, Timothy D., et al.
Publicado: (2014)

Adaptive Evolution of the FADS Gene Cluster within Africa
por: Mathias, Rasika A., et al.
Publicado: (2012)

Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases
por: Chilton, Floyd H., et al.
Publicado: (2017)

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans
por: Mathias, Rasika A, et al.
Publicado: (2011)

The impact of polyunsaturated fatty acid-based dietary supplements on disease biomarkers in a metabolic syndrome/diabetes population
por: Lee, Tammy C, et al.
Publicado: (2014)

Variants of the FADS1 FADS2 Gene Cluster, Blood Levels of Polyunsaturated Fatty Acids and Eczema in Children within the First 2 Years of Life
por: Rzehak, Peter, et al.
Publicado: (2010)

Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes
por: Rahbar, Elaheh, et al.
Publicado: (2018)

FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids
por: Reynolds, Lindsay M., et al.
Publicado: (2020)

Generation of Fad2 and Fad3 transgenic mice that produce n-6 and n-3 polyunsaturated fatty acids
por: Song, Lishuang, et al.
Publicado: (2019)

Association between FADS Gene Expression and Polyunsaturated Fatty Acids in Breast Milk
por: Tian, Huimin, et al.
Publicado: (2022)

Polymorphisms in Fatty Acid Desaturase (FADS) Gene Cluster: Effects on Glycemic Controls Following an Omega-3 Polyunsaturated Fatty Acids (PUFA) Supplementation
por: Cormier, Hubert, et al.
Publicado: (2013)

Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis
por: Chen, Hao Yu, et al.
Publicado: (2020)

Intake of n-3 polyunsaturated fatty acids in childhood, FADS genotype and incident asthma
por: Talaei, Mohammad, et al.
Publicado: (2021)

Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics
por: Arm, Jonathan P, et al.
Publicado: (2013)

Interpreting Clinical Trials With Omega-3 Supplements in the Context of Ancestry and FADS Genetic Variation
por: Chilton, Floyd H., et al.
Publicado: (2022)

Lower polyunsaturated fatty acid levels and FADS2 expression in adult compared to neonatal keratinocytes are associated with FADS2 promotor hypermethylation
por: Pararasa, C., et al.
Publicado: (2022)

Isolation and functional analyses of PvFAD2 and PvFAD3 involved in the biosynthesis of polyunsaturated fatty acids from Sacha Inchi (Plukenetia volubilis)
por: Yang, Tianquan, et al.
Publicado: (2020)

Investigation of Maternal Diet and FADS1 Polymorphism Associated with Long-Chain Polyunsaturated Fatty Acid Compositions in Human Milk
por: Niwa, Sakurako, et al.
Publicado: (2022)

Effect of FADS1 rs174556 Genotype on Polyunsaturated Fatty Acid Status: A Systematic Review and Meta-Analysis
por: Wu, Wen-Chieh, et al.
Publicado: (2023)

Single Nucleotide Polymorphisms in the FADS Gene Cluster but not the ELOVL2 Gene are Associated with Serum Polyunsaturated Fatty Acid Composition and Development of Allergy (in a Swedish Birth Cohort)
por: Barman, Malin, et al.
Publicado: (2015)

Impact of rs174537 on Critically Ill Patients with Acute Lung Injury: A Secondary Analysis of the OMEGA Randomized Clinical Trial
por: Dosso, Beverly, et al.
Publicado: (2020)

Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations
por: Yang, Chaojie, et al.
Publicado: (2021)

Dietary n-3 and n-6 polyunsaturated fatty acids, the FADS gene, and the risk of gastric cancer in a Korean population
por: Lee, Sunghee, et al.
Publicado: (2018)

Dietary ω3-and ω6-Polyunsaturated fatty acids reconstitute fertility of Juvenile and adult Fads2-Deficient mice
por: Stoffel, Wilhelm, et al.
Publicado: (2020)

Gene Expression of Desaturase (FADS1 and FADS2) and Elongase (ELOVL5) Enzymes in Peripheral Blood: Association with Polyunsaturated Fatty Acid Levels and Atopic Eczema in 4-Year-Old Children
por: Chisaguano, Aida Maribel, et al.
Publicado: (2013)

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World
por: Harris, Daniel N, et al.
Publicado: (2019)

Diet-Gene Interactions and PUFA Metabolism: A Potential Contributor to Health Disparities and Human Diseases
por: Chilton, Floyd H., et al.
Publicado: (2014)

Retention of fatty acyl desaturase 1 (fads1) in Elopomorpha and Cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in vertebrates
por: Lopes-Marques, Mónica, et al.
Publicado: (2018)

Age and Haplotype Variations within FADS1 Interact and Associate with Alterations in Fatty Acid Composition in Human Male Cortical Brain Tissue
por: Freemantle, Erika, et al.
Publicado: (2012)

Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study
por: Kim, Oh Yoen, et al.
Publicado: (2011)

FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome
por: Tian, Ye, et al.
Publicado: (2016)

MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells
por: Fan, Yongliang, et al.
Publicado: (2021)

Mechanisms of Omega-3 Polyunsaturated Fatty Acids in Prostate Cancer Prevention
por: Gu, Zhennan, et al.
Publicado: (2013)

Effect of polyunsaturated fatty acids on proliferation and survival of prostate cancer cells
por: Bratton, Brenden A., et al.
Publicado: (2019)

Association of polymorphisms in FADS gene with age-related changes in serum phospholipid polyunsaturated fatty acids and oxidative stress markers in middle-aged nonobese men
por: Hong, Seul Hee, et al.
Publicado: (2013)

Omega 3 polyunsaturated fatty acids inhibit cell proliferation by regulating cell cycle in fad3b transgenic mouse embryonic stem cells
por: Wei, Zhuying, et al.
Publicado: (2018)

Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight?
por: Zec, Manja M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_11pb026p8is8rhh6jhiv1sp7d8