Sublinear response in lacZ mutant frequency of Muta(™)Mouse spermatogonial stem cells after low dose subchronic exposure to N‐ethyl‐N‐nitrosourea

The transgenic rodent mutation assay was used to compare the dose–response relationship of lacZ mutant frequency (MF) in spermatogonial stem cells exposed acutely or subchronically to N‐ethyl‐N‐nitrosourea (ENU). Muta(™)Mouse males were exposed orally to 0, 25, 50, or 100 mg/kg ENU for acute exposur...

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Detalles Bibliográficos
Autores principales: O'Brien, Jason M., Walker, Mike, Sivathayalan, Ahalya, Douglas, George R., Yauk, Carole L., Marchetti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680333/
https://www.ncbi.nlm.nih.gov/pubmed/25598316
http://dx.doi.org/10.1002/em.21932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680333/
https://www.ncbi.nlm.nih.gov/pubmed/25598316
http://dx.doi.org/10.1002/em.21932

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