Cargando…

Migration promotes mutator alleles in subdivided populations

Mutator alleles that elevate the genomic mutation rate may invade nonrecombining populations by hitchhiking with beneficial mutations. Mutators have been repeatedly observed to take over adapting laboratory populations and have been found at high frequencies in both microbial pathogen and cancer pop...

Descripción completa

Detalles Bibliográficos
Autores principales: Raynes, Yevgeniy, Sniegowski, Paul D., Weinreich, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680344/
https://www.ncbi.nlm.nih.gov/pubmed/30632605
http://dx.doi.org/10.1111/evo.13681