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Migration promotes mutator alleles in subdivided populations
Mutator alleles that elevate the genomic mutation rate may invade nonrecombining populations by hitchhiking with beneficial mutations. Mutators have been repeatedly observed to take over adapting laboratory populations and have been found at high frequencies in both microbial pathogen and cancer pop...
Autores principales: | Raynes, Yevgeniy, Sniegowski, Paul D., Weinreich, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680344/ https://www.ncbi.nlm.nih.gov/pubmed/30632605 http://dx.doi.org/10.1111/evo.13681 |
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