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(1)H-NMR Metabolomics Identifies Significant Changes in Metabolism over Time in a Porcine Model of Severe Burn and Smoke Inhalation

Burn injury initiates a hypermetabolic response leading to muscle catabolism and organ dysfunction but has not been well-characterized by high-throughput metabolomics. We examined changes in metabolism over the first 72 h post-burn using proton nuclear magnetic resonance ((1)H-NMR) spectroscopy and...

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Detalles Bibliográficos
Autores principales: Hendrickson, Cole, Linden, Katharina, Kreyer, Stefan, Beilman, Gregory, Scaravilli, Vittorio, Wendorff, Daniel, Necsoiu, Corina, Batchinsky, Andriy I., Cancio, Leopoldo C., Chung, Kevin K., Lusczek, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680385/
https://www.ncbi.nlm.nih.gov/pubmed/31336875
http://dx.doi.org/10.3390/metabo9070142