Nanogels of Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Preparation, In Vitro Characteristics and Therapeutic Potential

A novel anionic nanogel system was prepared using succinylated glycol chitosan-succinyl prednisolone conjugate (S-GCh-SP). The nanogel, named NG(S), was evaluated in vitro and in vivo. S-GCh-SP formed a nanogel via the aggregation of hydrophobic prednisolone (PD) moieties and the introduced succinyl...

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Detalles Bibliográficos
Autores principales: Zhou, Haiyan, Ichikawa, Atsuko, Ikeuchi-Takahashi, Yuri, Hattori, Yoshiyuki, Onishi, Hiraku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680395/
https://www.ncbi.nlm.nih.gov/pubmed/31337090
http://dx.doi.org/10.3390/pharmaceutics11070333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680395/
https://www.ncbi.nlm.nih.gov/pubmed/31337090
http://dx.doi.org/10.3390/pharmaceutics11070333

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