Rapid Identification of Tanshinone IIA Metabolites in an Amyloid-β(1-42) Induced Alzherimer’s Disease Rat Model using UHPLC-Q-Exactive Qrbitrap Mass Spectrometry

Alzheimer’s disease (AD) is a neurodegenerative disorder that damages health and welfare of the elderly, and there has been no effective therapy for AD until now. It has been proved that tanshinone IIA (tan IIA) could alleviate pathological symptoms of AD via improving non-amyloidogenic cleavage of...

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Detalles Bibliográficos
Autores principales: Liang, Shuang, Wang, Zijian, Yuan, Jiaqi, Zhang, Jing, Dai, Xueling, Qin, Fei, Zhang, Jiayu, Sun, Yaxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680413/
https://www.ncbi.nlm.nih.gov/pubmed/31315255
http://dx.doi.org/10.3390/molecules24142584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680413/
https://www.ncbi.nlm.nih.gov/pubmed/31315255
http://dx.doi.org/10.3390/molecules24142584

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