Quantitative Prediction of Human Pharmacokinetics and Pharmacodynamics of CKD519, a Potent Inhibitor of Cholesteryl Ester Transfer Protein (CETP)

CKD519, a selective inhibitor of cholesteryl ester transfer protein(CETP), is undergoing development as an oral agent for the treatment of primary hypercholesterolemia and mixed hyperlipidemia. The aim of this study was to predict the appropriate efficacious dose of CKD519 for humans in terms of the...

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Detalles Bibliográficos
Autores principales: Choi, Suein, Han, Seunghoon, Jeon, Sangil, Yim, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680430/
https://www.ncbi.nlm.nih.gov/pubmed/31311144
http://dx.doi.org/10.3390/pharmaceutics11070336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680430/
https://www.ncbi.nlm.nih.gov/pubmed/31311144
http://dx.doi.org/10.3390/pharmaceutics11070336

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