Betulin Promotes Differentiation of Human Osteoblasts In Vitro and Exerts an Osteoinductive Effect on the hFOB 1.19 Cell Line Through Activation of JNK, ERK1/2, and mTOR Kinases

Although betulin (BET), a naturally occurring pentacyclic triterpene, has a variety of biological activities, its osteogenic potential has not been investigated so far. The aim of this study was to assess the effect of BET on differentiation of human osteoblasts (hFOB 1.19 and Saos-2 cells) in vitro...

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Detalles Bibliográficos
Autores principales: Mizerska-Kowalska, Magdalena, Sławińska-Brych, Adrianna, Kaławaj, Katarzyna, Żurek, Aleksandra, Pawińska, Beata, Rzeski, Wojciech, Zdzisińska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680433/
https://www.ncbi.nlm.nih.gov/pubmed/31331121
http://dx.doi.org/10.3390/molecules24142637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680433/
https://www.ncbi.nlm.nih.gov/pubmed/31331121
http://dx.doi.org/10.3390/molecules24142637

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