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Betulin Promotes Differentiation of Human Osteoblasts In Vitro and Exerts an Osteoinductive Effect on the hFOB 1.19 Cell Line Through Activation of JNK, ERK1/2, and mTOR Kinases
Although betulin (BET), a naturally occurring pentacyclic triterpene, has a variety of biological activities, its osteogenic potential has not been investigated so far. The aim of this study was to assess the effect of BET on differentiation of human osteoblasts (hFOB 1.19 and Saos-2 cells) in vitro...
Autores principales: | Mizerska-Kowalska, Magdalena, Sławińska-Brych, Adrianna, Kaławaj, Katarzyna, Żurek, Aleksandra, Pawińska, Beata, Rzeski, Wojciech, Zdzisińska, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680433/ https://www.ncbi.nlm.nih.gov/pubmed/31331121 http://dx.doi.org/10.3390/molecules24142637 |
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