Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Multicomponent Reactions and In Vitro–In Silico Studies Against SiHa, HeLa, and CaSki Human Cervical Carcinoma Cell Lines

A series of 12 polysubstituted pyrrolo[3,4-b]pyridin-5-ones were synthesized via a one-pot cascade process (Ugi–3CR/aza Diels-Alder/N-acylation/decarboxylation/dehydration) and studied in vitro using human epithelial cervical carcinoma SiHa, HeLa, and CaSki cell line cultures. Three compounds of the...

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Detalles Bibliográficos
Autores principales: Segura-Olvera, Daniel, García-González, Ailyn N., Morales-Salazar, Ivette, Islas-Jácome, Alejandro, Rojas-Aguirre, Yareli, Ibarra, Ilich A., Díaz-Cervantes, Erik, Alcaraz-Estrada, Sofía Lizeth, González-Zamora, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680468/
https://www.ncbi.nlm.nih.gov/pubmed/31336585
http://dx.doi.org/10.3390/molecules24142648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680468/
https://www.ncbi.nlm.nih.gov/pubmed/31336585
http://dx.doi.org/10.3390/molecules24142648

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